Three and Four Membered Heterocyclic Rings Substituted Derivatives of Phenobarbital and Using CPE for Determination of PB (II)

Abstract

A series of three and four member rings N-substituted Phenobarbital have been synthesized. The nitrogen atoms have been alkylated first to form N-carboxymethyl followed by cyclization reaction to form three and four heterocyclic rings. All the synthesized compounds have been identified using I.R, ¹H NMR, and then using its heterocyclic rings by determination of lead (II) by cloud point extraction (CPE) techniques.  

Keywords: 5, 5-substituted Phenobarbital, 1, 2-Diazetidine, 1,2-diaziridin, Cloud point extraction, Triton X-114.