The Relationship between the Aquatic Extracts of the Moringa Oleifera Seeds and the Genetic Expression of (SAP5) Gene in Candida albicans Accompanying Cancer Patients

Abstract

It has been detected gene expression using the Real – time technique for some Isolations Candida albicans before and during infection to cells epithelium, Ther esults be  high rate of gene expression (37.156 ±7.66049) to T2 treatment  and significantly difference at the level of the probability P ≤ 0.01 ,compared with the C treatment  that at a rate(1.040 ± 0.32229).As the use of an extract of the seeds of Moringa Oleifera In the concentration of 25% to assess its impact on the gene expression (SAP5) before and during infection yeast cells of epithelial and the results were reduced gene expression treatment T1 at a rate(0.074 ± 0.01542) comparison with the treatment C (1.040 ± 0.32229) and teams significantly at the level of the probability P ≤ 0.01, As for the T2 treatment was gene expression at a rate(37.156 ±7.66049) high Compared with T3 treatment in which gene expression dropped at a rate (19.565 ± 8.82162) and with a significant difference at the level of the probability of P ≤ 0.01.

 

Keywords:  Moringa Oleifera, SAP5gene, C.albicans, Candidiasis, Real-time PCR.