Synthesis, Spectroscopic Characterization, and Biological Evaluation of Some Transition Metal Complexes from C16H19N3O3S Ligand

Abstract

A first series of transition metal complexes were synthesized from the ligand Methyl -6- [2-(benzyl ideneamino) -2- (4-hydroxyphenyl) acetamido]-2, 2-dimethyl -5-oxo-1-thia 4-azabicyclo [3.2.0] heptane-3-carboxylate with appropriative metal salts. The complexes were characterized by spectral methods such as FTIR, Uv-Visible, and Atomic absorption as well as some physical properties, molar conductivity and magnetic moment measurements. The results showed that the proposed structures of these complexes are Octahedral, except Co ^II is a tetrahedral geometry. The biological activities of these complexes were studied using two types of bacteria (Staphylococcus aures, Echerchia coli) in addition to Candical albicans c. albicans that gave results a good activity than the free ligand.