Synthesis, Characterization and Biological Evaluation of Esters Derived from Sulfamethoxazole Drug

Abstract

A series of novel esters compounds have been prepared from the reaction of sulfamethoxazole drug with α-chloro acetyl chloride then reaction of the resulting compound with various carboxylic acids and carboxylic drugs. The modern ester has been diagnosed by ¹HNMR, FTIR spectral data and their physical properties and some of them were screened for their antibacterial activity.

Keywords: Sulfamethoxazole, Esters, Antibacterial activity.