Isolation of active compounds from aerial parts of Albizia Procera
Abstract
The purpose of the study is to isolate active compounds from herbal plants that have various effects on living systems. The plants are indispensable sources for both preventive and curative medicinal preparations of various traditional medicine systems practiced worldwide. Albizia species is used to treat anxiety, cancer, depression, insomnia, sore throat and to reduce swelling associated with trauma. Isolation of active constituents and pharmacological screening can assist us to find new therapeutically active drugs. The compound (1) 2,2- dimethylvinyl methyl ketone and compound (2) 2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexene (C30H50) are isolated from hexane and ethyl acetate fraction of albizia procera belonging to the family mimosoideae. The above isolated Compound (1) is an intermediate to synthesis a number of different types of organic compounds and Compound (2) showed potential hepatoprotective effect against drug induced hepatotoxicity. The structure of compound have been established [1] by IR, 1H NMR, 13C NMR and MASS spectrophotometry.
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Sudarma I.M, Supiani L, Syafitri A., et al., Synthesis of 5-Hydroxy-4-methoxy-α-methyl-(1,2-benzobutane sultone) from Eugenol and Eugenil acetate. Asian journal of chemistry. 2018; 30(11): 2411-2414.
Olaleye M.T, Adegboye O.O, Akindahunsi A.A. Alchornea cordifolia extract protects wistar albino rats against acetaminophen-induced liver damage. African Journal of Biotechnology. 2006; 5 (24): 2439-2445.
Chakrabatry T & Gangopadhyay M .The Genus Albizia In India. J.Econ.Taxon.Bot, 1996;20: 581-597.
Wu, T.L., Mimososideae. In: Fl.Reip.Pop.Sinicae, 1988;39, (leguminosae-1).
Gupta RK. Multipurpose trees for agroforestry and waste land utilisation. Multipurpose trees for agroforestry and waste land utilisation., 1993; xv + 562.
ICFRE. Albizia procera (Safed Siris). Extension Series. Dehra Dun, India: Indian Council of Forestry Research and Education (ICFRE); 1995.
Nielsen I. The Malesian species of Acacia and Albizia (Leguminosae-Mimosoideae). Opera Botanica., 1985; 81:1-50.
Valkenburg J.L.C.H van. Albizia procera. In: Fariday Hanum I, Maesen L.J.G vander, eds. Plant Resources of South-East Asia No. 11- Auxiliary Plants. Prosor Foundation, Bogor, Indonesia. Backhuys Publishers, Leiden, Netherlands: 1997; 65-68.
Anon. The useful plants of India. Publications & Information Directorate., CSIR, NewDelhi, India.,1986.
Asolker LV, Kakkar JJ, Chakre OJ, Supplement tn glossary of Indian medicinal plants. Part I (A-K). National institute of science and communication, New delhi: 2000;116-7.
Gupta RK. Multipurpose trees for agroforestry and wasteland utilization. Oxford & IBH Publishing Co. PVT. Ltd. 1992.
Kavitha J, Sivakrishnan S, Kottai muthu A. GC-MS analysis of ethanolic parts of aerial parts Albizia procera (Roxb.) Benth. International journal of pharmacy and pharmaceutical sciences, 2013; 5(3): 702-704.
Parotta JA, Roshetko JM. Albizia procera - white siris for reforestation and agroforestry.. Winrock International, 1997. FACT Net 97-01.
Parrotta JA. Albizia procera, White-siris, Tall albizia (Mimosaceae) Legume family. Rio Piedras, Institute of Tropical Forestry., 1984; SO-ITF-SM-6.
Wadsworth FH. Forest production for tropical America, United States Department of Agriculture. Agricultural Handbook., 1997; 710.
Browne F.G. Pests and diseases of forest plantations trees. Clarendon Press, Oxford., 1968.
Kirtikar, K.R. and Basu, B.D. Indian medicinal plants., Jayyed Press, New Delhi., 1975; 2(4).
List P.H and Horhammer L. Hager's handbuch der pharmazeutischen praxis., Springer-Verlag, Berlin., 1969-1979; vols 2–6.
Sivakrishnan S, Kottai muthu Evaluation of hepatoprotective activity of squalene isolated from Albizia procera against paracetamol induced hepatotoxicity on wistar rats. World journal of pharmacy and pharmaceutical sciences, 2014; 3(3): 1351-1362.
Aziz-ur-Rehman, Almas Sattar, Muhammad Athar Abbasi, Arslan Raza M, et al., Synthesis and structural analysis of persuasive antibacterial agents and enzyme inhibitors derived from 5-(1-(4-Tosyl)piperidin-4-yl)-1,3,4-oxidiazol-2-thiol. Asian journal of chemistry. 2017; 30(2): 260-264.
Shanthamani M, Ulagi R, Isolation of steroid compounds from randia malabarica and their biological activity. Asian journal of chemistry, 2019; 31(1): 135-138.
Zamakshshari N.H, Daud S, Teh S.S, Mah S.H et al., phytochemicals from calophyllum depressinervosum. Asian journal of chemistry. 2018; 30(5): 975-978.
He Liu, Fei-Fei Han, Li-Li Gong, Ya-Li Lv and Li-Hong Liu. Synthesis and crystal structure of 1,7,8,9-Tetrachloro-N-ethyl-10,10-dimethoxy-4-azatricyclo(5,2,1,02,6) dec-8-ene-3,5-dione. Asian journal of chemistry. 2015; 28(2): 295-297.
Azmir J, Zaidul I.S.M., et al. Techniques for exraction of bioactive compounds from plant materials : a review. Journal of food and engineering, 2013, 117; 426-436.
Kottai muthu A, Sivakrishnan S. Antioxidant potential, total phenolic and flavonoids content of aerial parts ethanolic parts of Albizia procera. Asian journal of pharmaceutical and clinical research. 2012; 6(1): 108-110.
Gangwal A, Parmar S.K, Seth N.R. Triterpenoid, flavonoids and sterols from Langenaria siceraria fruits. Scholars research library, Der Pharmacia Lettre, 2010;2(1); 307-317.
Edeoga H.O, Okwu D.E et al, Phytochemical constituents of some Nigerian plants. African journal of biotechnology. 2005;4(7): 685-688.
Imanzadeh G.H, Banaei A.R, Hashemi S and Soltanzadeh Z. Synthesis of new derivatives of spiro[9H-xanthene-oxindole] under solvent-free conditions. Asian journal of chemistry. 2016; 29(1): 45-51.
Babul kumari, Tirath kumar. Hepatoprotective effect of Vitamin C and E on antitubercular drugs induced hepatotoxicity in albino rats. Journal of Global Pharma Technology. 2018;10(8):12-18.
Oleg V.Gerush, Larsya V. Iakovlieva, Olena Yu. Koshova, Sergii O.Spiridonov. Investigation of the mechanism of action of new heptoprotective herbal drugs in the experiment. Journal of Global Pharma Technology. 2018;10(8):397-409.
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