Synthesis, Characterization, Antimicrobial Activity and Antioxidant of Azo Schiff Bases Containing Sulfanilamide

Abstract

Some new azo Schiff bases (SH₁-SH₆, SH₁₄) were prepared in good yields by reaction of Sulfanilamide with 2, 4-dihydroxy-5-(phenyldiazyl) benzaldehyde and its substituted derivatives (Z₁-Z₆, Z₁₄).  The structures of azo and azo-azomethine compounds were determined by FT-IR, ¹HNMR spectroscopic techniques, EI-mass and elemental analysis.  The azo-azomethine compounds have been tested in vitro against Pseudomonas aeruginosa (-Ve) gram and Staphylococcus sciuri (+ Ve) gram in order to assess their antibacterial characteristic. Antioxidant efficiency of the azo-azomethine compounds examined.

Keywords: Azo-azomethine, Azo compound, antioxidantand antibacterial activity, Sulfanilamide.