A Case Report on Diabetic Ketoacidosis in Children

Keerthana Chandrasekar, Diya C, Vignesh Kumar K

Abstract

Abstract:

Introduction: Diabetic Ketoacidosis (DKA) is a complex metabolic state characterized by hyperglycaemia, ketonemia and acidosis. It oocurs as a complication of diabetes that results in accumulation of ketone bodies and acidosis in large quantities in the blood. It occurs as a result of a complication of Type 1 Diabetes Mellitus (T1DM) and rarely in Type 2 Diabetes Mellitus (T2DM) in children and adult.

Presentation of the case: A 10 year old female child had the complaint of polyuria and polydipsia and within 2 weeks her weight has reduced to 10 kg; she also had itching, burning sensation during micturition and history of vomiting 2 episodes. She was diagnosed as T1DM with DKA and was treated with Intravenous Fluids, cefotaxime, ranitidine and insulin. She was re-admitted with complaints of fever, cough, headache and vomiting for which she was managed symptomatically and discharged.

Conclusion: DKA is found to be common; hence early diagnosis and proper education and public awareness should be initiated.

Key Words: Diabetic Ketoacidosis, Children, Polydipsia, Polyuria, Type 1 Diabetes Mellitus

 

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References

[Internet]. Ucdenver.edu. 2019 [cited 8 October 2019]. Available from: http://www.ucdenver.edu/academics/colleges/medicalschool/centers/BarbaraDavis/education/resources/Documents/BDC%20DKA%20Treatment%20Protocol%202018-19.pdf

Pihoker C, Koves I, Glaser N. Diabetic Ketoacidosis. Pediatric Critical Care. 2011;:1124-1130.

Mulliqi Kotor V, Gashi N, Toro H. SEVERE KETOACIDOSIS AT ONSET OF TYPE 1 DIABETES INCHILDREN DUE TO LATE DIAGNOSIS. Diabetologia Croatica.2007;: 36-3.

Dunger D, Sperling M, Acerini C, Bohn D, Daneman D, Danne T et al. European Society for Paediatric Endocrinology/Lawson Wilkins Pediatric Endocrine Society Consensus Statement on Diabetic Ketoacidosis in Children and Adolescents. PEDIATRICS. 2004;113(2):e133-e140.

Raghupathy P. Diabetic ketoacidosis in children and adolescents. Indian Journal of Endocrinology and Metabolism. 2015;19(7):55.

Seifter J. Acid-Base Disorders. Goldman's Cecil Medicine. 2012;:741-753.

Wolfsdorf J, Glaser N, Agus M, Fritsch M, Hanas R, Rewers A et al. ISPAD Clinical Practice Consensus Guidelines 2018: Diabetic ketoacidosis and the hyperglycemic hyperosmolar state. Pediatric Diabetes. 2018;19:155-177.

Diabetic Ketoacidosis (DKA) - Endocrine and Metabolic Disorders - MSD Manual Professional Edition [Internet]. MSD Manual Professional Edition. 2019 [cited 8 October 2019]. Available from: https://www.msdmanuals.com/en-in/professional/endocrine-and-metabolic-disorders/diabetes-mellitus-and-disorders-of-carbohydrate-metabolism/diabetic-ketoacidosis-dka

Helman A, Helman A. Pediatric DKA | Emergency Medicine Cases [Internet]. Emergency Medicine Cases. 2019 [cited 8 October 2019]. Available from: https://emergencymedicinecases.com/pediatric-dka/

Wolfsdorf J, Glaser N, Sperling M. Diabetic Ketoacidosis in Infants, Children, and Adolescents: A consensus statement from the American Diabetes Association. Diabetes Care. 2006;29(5):1150-1159.

Chaudhry S. Hyperglycemic emergencies: diabetic ketoacidosis and hyperosmolar hyperglycemia state | McMaster Pathophysiology Review [Internet]. Pathophys.org. 2019 [cited 8 October 2019]. Available from: http://www.pathophys.org/hyperglycemic-emergencies-diabetic-ketoacidosis-and-hyperosmolar-hyperglycemia-state/

Fenichel G. Altered States of Consciousness. Clinical Pediatric Neurology [Internet]. 2009 [cited 30 January 2019]. Available from: https://doi.org/10.1016/B978-1-4160-6185-4.00002-2

Park J, Shin S, Shim Y, Choi J, Kim H. Multiple daily injection of insulin regimen for a 10-month-old infant with type 1 diabetes mellitus and diabetic ketoacidosis. Annals of Pediatric Endocrinology & Metabolism. 2016;21(2):96.

Hekkala A, Reunanen A, Koski M, Knip M, Veijola R. Age-Related Differences in the Frequency of Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents. Diabetes Care. 2010;33(7):1500-1502.

Maletkovic J, Drexler A. Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State. 2019.

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