Rationality and Prescribing Pattern of Antimicrobials on Female Lower Genital Tract Infection in a Tertiary Care Hospital of Odisha

Ginia Agasti, Rasmita Jena, Dipti rani Rath, Trupti Rekha Swain, Goutam Ghosh, Durga Madhab Kar

Abstract

Objective: Current study is based on the pattern analysis of various antimicrobial prescriptions for the treatment of female lower genital tract infection and its validation of rational use in a tertiary care hospital of Odisha. Methods: The current prospective investigation was carried out in outpatient department of Obstetrics and Gynaecology department at a tertiary care hospital over a period of six months.   A suitable data collection was carried out from female lower genital tract infection patients who were of 11-55 years of age group. Results: The study result found that most commonly prescribed antimicrobials were antifungal (azoles derivatives) and its combination with other antimicrobials. The other antimicrobials include, topical (8.4%)/single antimicrobial oral (2.8%)/ combination (intravaginal as well as oral- 50%) followed by other antimicrobials like linozolid (4.8%). Our study reveals that, antifungal agents are the most common antimicrobial drugs prescribed on the basis of laboratory diagnosis report, which revealed that, staphylococcal infection in majority of the patients (42%). Conclusion: Hence, present study shall definitely provide a small initiative towards control of emergence of antibacterial resistance, its side effects and cost of therapy worldwide.

Keywords: Prescribing pattern, Antimicrobials, Lower genital tract infection, Tertiary care hospital.

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References

Dumoulin J, Kaddar M, Velásquez G. Access to drugs and finance: basic economic and financial analysis. Geneva, World Health Organization; 1991.

Tripathi KD. Aspects of pharmacotherapy; clinical pharmacology and drug development. In: Essentials of medical pharmacology. 6th edition. New Delhi: Jaypee Brothers; 2008:68-71.

C. M. Gonzalez and A. J. Schaeffer, “Treatment of urinary tract infection: what’s old, what’s new, and what works,” World Journal of Urology, vol. 17, no. 6, pp. 372–382, 1999.

Johnson, C. C. Definitions, classification, and clinical presentation of urinary tract infections. Med. Clin. North Am. 75, 241–252 (1991).

Stefano Salvatore, Silvia Salvatore, Elena Cattoni, Gabriele Siesto, Maurizio Serati, Paola Sorice, Marco Torella. European Journal of Obstetrics & Gynecology and Reproductive Biology 156 (2011) 131–136.

Tomas L, Griebling, Urinary Tract Infection in Women. Urologic diseases in America, Journal of urology 2003:589-618.

Sujata Priyadarsini Mishra, Ratna Panda, Tapan Patnaik, Mahesh Chandra Sahu. Surveillance Of Microbial Flora For Infertility Couples In An Indian Tertiary Care Teaching Hospital. Asian J Pharm Clin Res, Vol 10, Issue 4, 2017, 405-408.

Foxman, B. The epidemiology of urinary tract infection. Nat. Rev. Urol. 7, 653–660 (2010).

Gupta K, Trautner BW. Urinary tract infections, pyelonephritis, and prostatitis. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J, editors. Harrison’s Principles of Internal Medicine. 19th ed. New York: McGraw Hill Education; 2015. p. 861-4.

Selvaraj R. Prospective assessment of antimicrobial prescribing pattern at a tertiary care hospital. Al Ameen J Med Sci; Volume 8, No.4, 2015. 276-280.

Sharma M, Eriksson B, Marrone G, Dhaneria S, Lundborg CS. Antibiotic prescribing in two private sector hospital; one teaching and one non-teaching : A cross-sectional study in Ujjain, India. BMC Infect Dis. 2012; 12:155.

Kritirekha M., Swayansidha, M. & Subhra G., Management of Persistent Vaginal Discharge. Pp.1-3.

Das A K, Roy K, Kundu K K, Das N, Islam C N, Ram A K, Banerjee S N, Chaudhuri SB, Dutta S, Munshi S. Study of rational utilization and cost analysis of antimicrobials in a government teaching hospital. Indian J Pharmacol. 2002. 34, 59-61.

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